Trout Run is an unincorporated community in Lycoming County, Pennsylvania, United States. It is located at the southern terminus of PA 14, at its interchange with US 15. Nearby current or historic communities include: Buttonwood Calvert Cascade Cogan House Fields Station Gamble Kelleysburg Marsh Hill Pleasant Stream Wallis Run White Pine Trout Run is also the name of several different streams and rivers in Pennsylvania.